LongARGXAugust 31, 2026

Janus Henderson Capital Funds Plc - Global Life Sciences Fund on argenx SE

Thesis

Argenx was a leading contributor during August following positive phase 3 results for Vyvgart in autoimmune myositis. The treatment significantly improved muscle strength and physical function compared with placebo. The benefits were rapid and sustained and the trial achieved a statistically significant outcome, reinforcing the clinical case for the product.

Vyvgart significantly improved muscle strength and physical function in adults with autoimmune myositis.
Janus Henderson Capital Funds Plc - Global Life Sciences Fund — Global Life Sciences Fund Monthly Commentary

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